Great TED Talk by Stuart Firestein called The Pursuit of Ignorance:
He gives a course at Columbia called Ignorance and I love how in his model, knowledge leads to “better” ignorance and not the reverse. In this age of readily available facts on Google and Wikipedia, the role of universities is to articulate meaningful questions that science will chip at. He uses the analogy of ripples on a pond, where knowledge is a drop in the human experience and the ripples represent the extent of our knowledge. Science and academic research aims to work beyond the edges of these ripples, in the nether regions where ignorance lies.